The Virtual Brain

46 EduCases for The Virtual Brain.

Learning by doing.

Simulating the human brain is the holy grail of neuroscience – offering a pioneering tool for understanding how our brain works and how to deal with its disorders like stroke, epilepsy or neurodegenerative diseases like Alzheimer’s or Parkinson’s.

While large-scale research initiatives simulate neurons and small brain regions at the cellular level on massively parallel hardware, they are still years away from clinical applications.

The Virtual Brain (TVB) takes a different approach and reduces complexity on the micro level to attain the macro organization: a TVB model of a patient's brain generates sufficiently accurate EEG, MEG, BOLD and SEEG signals by reducing the complexity millionfold through methods from statistical physics. The key is TVB’s hybrid approach of merging individual anatomy from brain imaging data with state-of-the-art mathematical modeling.

In a nutshell:
you can simulate a human brain with TVB right now, for free and with access to the source code – on average MacBooks, faculty Linux servers or supercomputers like Piz Daint in CSCS Lugano.

Since its early beginnings as network equations scribbled on a bar coaster in 2008, TVB has gained wide recognition – demonstrated by regular invitations to participate at neuroinformatics events such as INCF conferences, and workshops dedicated to High Performance Computing (HPC) (such as organized by NSG).

Today, TVB is a reference tool for full-brain simulation. TVB serves as the simulation engine in the world’s first clinical trial on predictive brain modeling in epilepsy surgery (EPINOV). TVB is also the choice of full-brain simulator in Europe’s digital research infrastructure EBRAINS and directly links to other large-scale neuroinformatics efforts such as the Allen Institute’s Mouse atlas or the Human Brain Project (HBP).

A large, growing user base of clinicians and scientists are working every day with TVB, citing its scientific groundwork in well over 100 peer-reviewed publications. Dedicated research facilities at Charité in Berlin, AMU in Marseille and Baycrest in Toronto have constructed and simulated almost 1000 individual, Connectome-based brain network models and published their findings, clocking in upwards of 10 million CPU core hours.

Past events

New developments

  • TVB v2 blog illustration

    BIG new release: The Virtual Brain version 2.2

    April 1

    Our scientists and developers are very proud to announce the next generation of The Virtual Brain: version 2.2! Many core parts of the software have been rewritten to make it faster, cleaner, shorter, much more powerful and just overall nicer!

    First thing: upgrade existing installations from v1.5.8

    TVB 2.2 has a new storage architecture underneath. Your data will be migrated automatic

  • McGill Summer School: The Virtual Brain lecture and workshop

    March 23

    Learn to use The Virtual Brain: Lectures with subsequent hands on session at the McGill Summer School in Nonlinear Dynamics for the Life Sciences with Applications to Neuroscience and Psychology.

    Registration is open!

    Find out more here

  • Brain Modeling Service image

    TVB-EBRAINS Integrated Workflows - 4th Virtual Workshop

    March 1

    TVB-EBRAINS Integrated Workflows - 4th Virtual Workshop will be held on March 12th at 9am to 15:00 CET.

    The purpose of this workshop series is to discuss interfaces and workflows of The Virtual Brain (TVB) in the EU Flagship’s Research Infrastructure EBRAINS.

    To register please use the form below.

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  • BIDS Extension Proposal: Computational Model Specifications - Contributions Welcome!

    February 16

    Brain Imaging Data Structure [BIDS] is a community effort to define standards in data / metadata. Please contribute to this proposal which extends the original specification to further integrate different kinds of data, such as imaging methods we use for brain visualisation and simulation.

    You can find the draft document here, and all are welcome to add suggestions to this draft: [BIDS extensi

  • 5th HBP Student Conference on Interdisciplinary Brain Research

    January 18

    We are pleased to announce the 5th HBP Student Conference on Interdisciplinary Brain Research.

    Don't miss the keynote lecture by Petra Ritter on February 1st and the Virtual Brain Cloud Workshop on February 2nd.

  • TVB_EduPack_blog_cover.jpeg

    TVB EduPack offers video lectures with step-by-step instructions for using The Virtual Brain

    January 12

    For several years, a growing number of video lectures on using The Virtual Brain software have been posted on various websites and YouTube playlists. We've collected the best ones, added annotations, linked them with publications and notebooks and bundled them all into the TVB EduPack!

    Our new NewsWire section starts with [46 hand-picked TVB EduCases](/tvb/zwei/newswire-educase "Visit

  • New Alpha Release: TVB version 2.1a1

    January 5

    The Virtual Brain is gearing up towards a big new release in summer 2021! Core parts of the software have been completely rewritten to enable easier usage for scripting users, make room for exciting new features and be much, much faster!

    Today we're offering an Alpha release of TVB 2.1a1 for direct download & testing:

    • Download for Windows (1 GB)
    • Download for macOS (750 MB)*
  • Register for our Online Course running from Dec 2020 to Feb 2021 - “Personalized Multi-scale Brain Simulation”

    November 20

    For registration to this course please contact petra.ritter at

    Course Content

    This course provides basic knowledge on personalized brain network modeling and will include both lectures and tutorials. The course will include 120 hours of work, including both contact hours and individual study. Required interdisciplinary methods will be introduced. A focus will be se