The Virtual Brain

46 EduCases for The Virtual Brain.

Learning by doing.

Simulating the human brain is the holy grail of neuroscience – offering a pioneering tool for understanding how our brain works and how to deal with its disorders like stroke, epilepsy or neurodegenerative diseases like Alzheimer’s or Parkinson’s.

While large-scale research initiatives simulate neurons and small brain regions at the cellular level on massively parallel hardware, they are still years away from clinical applications.

The Virtual Brain (TVB) takes a different approach and reduces complexity on the micro level to attain the macro organization: a TVB model of a patient's brain generates sufficiently accurate EEG, MEG, BOLD and SEEG signals by reducing the complexity millionfold through methods from statistical physics. The key is TVB’s hybrid approach of merging individual anatomy from brain imaging data with state-of-the-art mathematical modeling.

In a nutshell:
you can simulate a human brain with TVB right now, for free and with access to the source code – on average MacBooks, faculty Linux servers or supercomputers like Piz Daint in CSCS Lugano.

Since its early beginnings as network equations scribbled on a bar coaster in 2008, TVB has gained wide recognition – demonstrated by regular invitations to participate at neuroinformatics events such as INCF conferences, and workshops dedicated to High Performance Computing (HPC) (such as organized by NSG).

Today, TVB is a reference tool for full-brain simulation. TVB serves as the simulation engine in the world’s first clinical trial on predictive brain modeling in epilepsy surgery (EPINOV). TVB is also the choice of full-brain simulator in Europe’s digital research infrastructure EBRAINS and directly links to other large-scale neuroinformatics efforts such as the Allen Institute’s Mouse atlas or the Human Brain Project (HBP).

A large, growing user base of clinicians and scientists are working every day with TVB, citing its scientific groundwork in well over 100 peer-reviewed publications. Dedicated research facilities at Charité in Berlin, AMU in Marseille and Baycrest in Toronto have constructed and simulated almost 1000 individual, Connectome-based brain network models and published their findings, clocking in upwards of 10 million CPU core hours.

Past events

New developments

  • HDC multiscale illus

    EBRAINS HealthDataCloud – a secure distributed health data platform

    November 2

    Founding on EOSC project Virtual Brain Cloud Charite now leads EBRAINS’ Health Data Cloud –- a GDPR-compliant, federated research data ecosystem that enables neuroscience research consortia across Europe and beyond to work with sensitive neuroscience data originating from human subjects, as well as defined routes for sharing of the data and results.

    Enabling the integration of distributed heal

  • TVB HBP Innovation Award 2021 Cover

    Viktor Jirsa and the Virtual Epileptic Patient (VEP) team win Human Brain Project Innovation Award

    July 23

    In January 2021, the Human Brain Project has launched the HBP Innovation Awards to recognize project researchers in their role of “innovators”. The awards will give internal and external visibility to their efforts towards the exploitation of their research results.

    The first Innovatio

  • Collaboration: The Virtual Brain Cloud, EBRAINS and AI-MIND

    July 1

    The Virtual Brain Cloud, EBRAINS and AI-MIND have formed a key strategic collaboration towards AI revolution in brain health care.

    Find out more here.

  • New Release: TVB version 2.3

    June 28

    This release brings over 20 improvements including bug fixes and dependencies upgrades. It's available for download for all supported platforms!

    Head over to our download page and get your update now!

    • Optimizations in framework: simulation run, Operations and Data structure page load
    • Start support for BIDS data: new button on
  • CNS*2021 Workshop

    June 20

    At CNS*2021 we will be holding a workshop on "Training resources for cross initiative data-driven modeling workflows".

    Prof Petra Ritter will introduce training resources for The Virtual Brain.

    July 6 at 10-13:30 EDT / 16-19:30 CEST.

    Registration here

  • 6th TVB-EBRAINS Integrated Workflows Workshop

    June 9

    TVB-EBRAINS Integrated Workflows - 6th Virtual Workshop will be held on September 3rd from 1200 to 1500 CEST.

    The purpose of this Workshop Series is to discuss existing interfaces and workflows of TVB in ERRAINS that have been developed in SGA2 and those under development or being planned for SGA3.

    The agenda is still forthcoming, however amongst other topics, we will discuss the [BIDS

  • European Institute for Theoretical Neuroscience (EITN) Workshop

    June 9

    Learn about TVB-integrated workflows in upcoming European Institute for Theoretical Neuroscience (EITN) workshop Computational Neuroscience in EBRAINS on June 10th.

    Register [here](

  • TVB-Fac-Hub

    EBRAINS TVB Facility Hub

    June 8

    The Virtual Brain Facility Hub at Aix-Marseille University will provide expert support for activities linked to the use of The Virtual Brain. The Hub aims to increase the capacity of neuroscientists to use ICT tools, such as TVB and EBRAINS, in order to advance scientific knowledge and facilitate the translation of research into clinical applications. To find out more, [Click Here](